Articles

(Original title: What size shirt do ‘Hispanics’ wear?) In 2008, an entrepreneur named Seph Skerritt was frustrated with the way he shopped for clothes. Then a student at MIT’s Sloan School of Management, he chafed at the time wasted while trying on garments in stores. Often, he thought, you settled on an ill-fitting item just to get the drudgery over with. While on an internship in Asia, Skerritt had enco

Some of the disparity in the risk from BRCA mutations is generational. One repeated finding is that, by age 50, mutation carriers born in the early twentieth century seem to have a lower risk of cancer than those born later3. The pattern suggests that outside influences interact with genes, and that something in the environment has changed in an unfavourable way. If researchers can figure out what those influences ar

For the microbiologist Justin Sonnenburg, that career-defining moment—the discovery that changed the trajectory of his research, inspiring him to study how diet and native microbes shape our risk for disease—came from a village in the African hinterlands. A group of Italian microbiologists had compared the intestinal microbes of young villagers in Burkina Faso with those of children in Florence, Italy. The villagers,

I have a piece in the NYT Sunday Review exploring the question: Should we bank our own stool for microbial reconstitution? A few notes and interesting tidbits that didn’t make it into the piece. First, an interesting study linking early-life microbial disturbances with the later development of asthma was just published in Science Translational Medicine. Unlike other studies, which look backward in time to make

Eugene Rosenberg, a coral microbiologist, ran into a rather large problem in the early 2000s. While working at the University of Tel Aviv in Israel, he discovered that he couldn’t replicate his own breakthrough findings from a decade earlier. What seemed like a potentially devastating failure at the time would lead Rosenberg to a new way of thinking about evolution. In the 1990s, he’d discovered a driver of coral dis

AS many as one in three Americans tries to avoid gluten, a protein found in wheat, barley and rye. Gluten-free menus, gluten-free labels and gluten-free guests at summer dinners have proliferated. Some of the anti-glutenists argue that we haven’t eaten wheat for long enough to adapt to it as a species. Agriculture began just 12,000 years ago, not enough time for our bodies, which evolved over millions of years, prima

The bomb that shattered Travis Adams’s peace of mind never actually exploded. Its timer went off, but the bomb malfunctioned. Still, the 25-year-old U.S. marine remained haunted by the memory of an explosive device diabolically concealed beneath a tempting array of cookies and candies. Whoever had set it that day in Iraq must have planned to blow up children. “People are evil if they’re willing to do that

Last year, asmy wife and I prepared for the arrival of our second child, I began to worry. My wife is a mid-level manager at an advertising agency with offices around the world. She heads a team, and she’s ferociously dedicated to her work—which translated, late in her pregnancy, to a couple of 80-hour weeks and chronic sleep deprivation. When she came home from work at 2 a.m. for the second time in as many weeks, I

In the mid-2000s Harry Sokol, a gastroenterologist at Saint Antoine Hospital in Paris, was surprised by what he found when he ran some laboratory tests on tissue samples from his patients with Crohn’s disease, a chronic inflammatory disorder of the gut. The exact cause of inflammatory bowel disease remains a mystery. Some have argued that it results from a hidden infection; others suspect a proliferation of cer