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When John Wick and his wife, Peggy Rathmann, bought their ranch in Marin County, Calif., in 1998, it was mostly because they needed more space. Rathmann is an acclaimed children’s book author — “Officer Buckle and Gloria” won a Caldecott Medal in 1996 — and their apartment in San Francisco had become cluttered with her illustrations. They picked out the 540-acre ranch in Nicasio mostly for its large barn, which they

I have a piece in the NYT Mag on the community of people who self-treat with parasites. They operate almost entirely outside of any regulatory or medical oversight. This is a story about desperate people trying to cure themselves with an unproven therapy. It’s not a story about whether the therapy works. We don’t know if it does. And in fact, there’s good evidence, in the form of double-blinded placebo-controlled stu

Some of the disparity in the risk from BRCA mutations is generational. One repeated finding is that, by age 50, mutation carriers born in the early twentieth century seem to have a lower risk of cancer than those born later3. The pattern suggests that outside influences interact with genes, and that something in the environment has changed in an unfavourable way. If researchers can figure out what those influences ar

For the microbiologist Justin Sonnenburg, that career-defining moment—the discovery that changed the trajectory of his research, inspiring him to study how diet and native microbes shape our risk for disease—came from a village in the African hinterlands. A group of Italian microbiologists had compared the intestinal microbes of young villagers in Burkina Faso with those of children in Florence, Italy. The villagers,

I have a piece in the NYT Sunday Review exploring the question: Should we bank our own stool for microbial reconstitution? A few notes and interesting tidbits that didn’t make it into the piece. First, an interesting study linking early-life microbial disturbances with the later development of asthma was just published in Science Translational Medicine. Unlike other studies, which look backward in time to make

Eugene Rosenberg, a coral microbiologist, ran into a rather large problem in the early 2000s. While working at the University of Tel Aviv in Israel, he discovered that he couldn’t replicate his own breakthrough findings from a decade earlier. What seemed like a potentially devastating failure at the time would lead Rosenberg to a new way of thinking about evolution. In the 1990s, he’d discovered a driver of coral dis

I have a piece on “gluten myths” in the NYT Sun Review. It’s received a fair amount of attention. And I’ve received a few unhappy emails. So a few clarifications: The piece in no way argues that people who have problems with gluten shouldn’t go on a gluten free diet. In fact, it acknowledges the robust evidence of a real increase over time in celiac disease. And although this isn’t

IN THE SUMMER OF 2010, Ben Blackwell, a five-year-old living near Dublin, Ireland, began complaining of headaches and a squealing noise in his head. And even though he’d stopped taking naps three years earlier, he now randomly fell asleep—while watching television, reading a book, sitting in the car. When Ben’s parents, James and Natalie, succeeded in rousing him, he often snarled at them and seemed terrified. But a

I have a piece in the NYT Sunday Review on the neurological problems sometimes associated with celiac disease. So, in case it’s not clear: The piece does not argue that gluten causes autism or mental illness. Rather, it points out that some cases of undiagnosed celiac can resemble these disorders.  As for the possible link with schizophrenia — still quite hypothetical — but here’s some additio

My Latest in the NYT on how casino money improved mental health outcomes of Cherokee children in North Carolina.